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Acupuncture alone reduced tumor volume of breast cancer in a mouse model


Journal: Zhongguo Zhong Xi Yi Jie He Za Zhi. 1995 Oct;15(10):615-7.


Manuscript title: Effect of acupuncture on immunologic function and histopathology of transplanted mammary cancer in mice. [Article in Chinese]


Abstract


This experiment mainly describes the effects of acupuncture on immunologic function and histopathology of transplanted mammary cancer in mice. The results were as follows: in acupuncture group, NK cell activity and T-lymphocyte positive rate of acid alpha-naphthyl acetate esterase (ANAE) and lymphocyte transformation rate were all increased. Compared with the control group, there was a significant difference (P < 0.01). The difference was insignificant, when compared with normal group (P > 0.05). Comparing the pathology grading of acupuncture group with control group, it showed marked difference in pathological section (P < 0.01). Adenoid structure and the degree of lymphocytic infiltration also have marked difference between acupuncture and control group (P < 0.05). Less tumor volume in acupuncture than control group were observed (P < 0.01). This indicated that acupuncture might increase the immunologic function of transplanted mammary cancer in mice and inhibit the growth of mammary cancer and enhance both differentiation level of mammary cancer cells and lymphocytic infiltration. Possibly acupuncture might reduce the malignancy of mammary cancer cells.


My Comments:


This article is cited by National Cancer Institute, which is the first report showing that acupuncture on points of non-breast can reduce growth of tumor. The mechanism of remote acupuncture points to reduce tumor volume is probably related its change of tumor microenvironment.


Reference:


https://pubmed.ncbi.nlm.nih.gov/8704430/

https://www.cancer.gov/about-cancer/treatment/cam/hp/acupuncture-pdq#_25

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