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Digestive
Disorders
Clinical Evidence and Scientific Mechanism
Accumulating evidence showed that acupuncture is helpful but not limited to the following digestive disorders:
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Irritable bowel syndrome
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Crohn’s disease
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Ulcerative colitis
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Gastroesophageal reflux disease (resource other than acupuncture)
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Biliary syndrome
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Cirrhosis



Acupuncture, electroacupuncture, and moxibustion have been shown to have several beneficial effects in rats with TNBS-induced colitis, including (1) improving weight loss and diarrhea; (2) ameliorating inflammatory profiles with reduction of neutrophil myeloperoxidase activity (MPO), decrease of inducible nitric oxide synthase expression, increase of serum IL-10, and downregulation of serum TNF-α and IL1-β and colonic TNF-α mRNA expression; and (3) attenuating adhesion and macroscopic damage scores.
IBS: Irritable bowel syndrome; AQP: Aquaporins.
Action mechanisms of acupuncture-moxibustion for IBS include the regulation of gastrointestinal motility, visceral hypersensitivity, brain-gut axis, neuroendocrine, and immunity.
Representative References:
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Ma XP, et al. Acupuncture-moxibustion in treating irritable bowel syndrome: How does it work? World J Gastroenterol 2014; 20(20): 6044-6054
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Song G, et al. Acupuncture in Inflammatory Bowel Disease. Inflammatory Bowel Diseases 2019; 25(7): 1129–1139.
